Tristetraprolin Overexpression in Gastric Cancer Cells Suppresses PD-L1 Expression and Inhibits Tumor Progression by Enhancing Antitumor Immunity

The RNA-binding protein tristetraprolin (TTP) binds to adenosine-uridine AU-rich elements in the 3′-untranslated region of messenger RNAs and facilitates rapid degradation of the target mRNAs. Therefore, it regulates the expression of multiple cancer and immunity-associated transcripts. Furthermore,...

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Detalles Bibliográficos
Autores principales: Guo, Jian, Qu, Huiheng, Shan, Ting, Chen, Yigang, Chen, Ye, Xia, Jiazeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078856/
https://www.ncbi.nlm.nih.gov/pubmed/29936792
http://dx.doi.org/10.14348/molcells.2018.0040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078856/
https://www.ncbi.nlm.nih.gov/pubmed/29936792
http://dx.doi.org/10.14348/molcells.2018.0040

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