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A Distance-Dependent Distribution of Presynaptic Boutons Tunes Frequency-Dependent Dendritic Integration

How presynaptic inputs and neurotransmitter release dynamics are distributed along a dendritic tree is not well established. Here, we show that presynaptic boutons that form onto basal dendrites of CA1 pyramidal neurons display a decrease in active zone (AZ) size with distance from the soma, resulti...

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Detalles Bibliográficos
Autores principales: Grillo, Federico W., Neves, Guilherme, Walker, Alison, Vizcay-Barrena, Gema, Fleck, Roland A., Branco, Tiago, Burrone, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078905/
https://www.ncbi.nlm.nih.gov/pubmed/29983327
http://dx.doi.org/10.1016/j.neuron.2018.06.015