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Notch3/VEGF-A axis is involved in TAT-mediated proliferation of pulmonary artery smooth muscle cells: Implications for HIV-associated PAH

The incidence of pulmonary arterial hypertension (PAH) is a significant co-morbidity observed in HIV (+) individuals. Pulmonary artery smooth muscle cells (PASMCs)—key components of the arterial vessel wall that regulate vessel diameter, demonstrate increased proliferation and hypertrophy in the lun...

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Detalles Bibliográficos
Autores principales: Guo, Ming-Lei, Kook, Yeon Hee, Shannon, Callen E., Buch, Shilpa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078940/
https://www.ncbi.nlm.nih.gov/pubmed/30109141
http://dx.doi.org/10.1038/s41420-018-0087-9