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Metabolic engineering using iterative self-cloning to improve lipid productivity in Coccomyxa
We previously developed a self-cloning system that introduces cDNA of the uridine monophosphate synthase gene (cUMPS) of Coccomyxa sp. strain Obi as a selectable marker into uracil-auxotrophic mutants (Ura(−)) of the same alga. Here, we developed a Cre/loxP-based system for the removal of cUMPS flan...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078956/ https://www.ncbi.nlm.nih.gov/pubmed/30082815 http://dx.doi.org/10.1038/s41598-018-30254-7 |