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Breast cancer diagnosed during pregnancy is associated with enrichment of non-silent mutations, mismatch repair deficiency signature and mucin mutations

Breast cancer diagnosed during pregnancy (BCP) is a rare and highly challenging disease. To investigate the impact of pregnancy on the biology of breast cancer, we conducted a comparative analysis of a cohort of BCP patients and non-pregnant control patients by integrating gene expression, copy numb...

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Detalles Bibliográficos
Autores principales: Nguyen, Bastien, Venet, David, Azim, Hatem A., Brown, David, Desmedt, Christine, Lambertini, Matteo, Majjaj, Samira, Pruneri, Giancarlo, Peccatori, Fedro, Piccart, Martine, Rothé, Françoise, Sotiriou, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078984/
https://www.ncbi.nlm.nih.gov/pubmed/30109263
http://dx.doi.org/10.1038/s41523-018-0077-3