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Somatic loss of WWOX is associated with TP53 perturbation in basal-like breast cancer

Inactivation of WW domain-containing oxidoreductase (WWOX), the gene product of the common fragile site FRA16D, is a common event in breast cancer and is associated with worse prognosis of triple-negative breast cancer (TNBC) and basal-like breast cancer (BLBC). Despite recent progress, the role of...

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Detalles Bibliográficos
Autores principales: Abdeen, Suhaib K., Ben-David, Uri, Shweiki, Aya, Maly, Bella, Aqeilan, Rami I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079009/
https://www.ncbi.nlm.nih.gov/pubmed/30082886
http://dx.doi.org/10.1038/s41419-018-0896-z