Salvage of the 5-deoxyribose byproduct of radical SAM enzymes

5-Deoxyribose is formed from 5′-deoxyadenosine, a toxic byproduct of radical S-adenosylmethionine (SAM) enzymes. The degradative fate of 5-deoxyribose is unknown. Here, we define a salvage pathway for 5-deoxyribose in bacteria, consisting of phosphorylation, isomerization, and aldol cleavage steps....

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Detalles Bibliográficos
Autores principales: Beaudoin, Guillaume A. W., Li, Qiang, Folz, Jacob, Fiehn, Oliver, Goodsell, Justin L., Angerhofer, Alexander, Bruner, Steven D., Hanson, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079011/
https://www.ncbi.nlm.nih.gov/pubmed/30082730
http://dx.doi.org/10.1038/s41467-018-05589-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079011/
https://www.ncbi.nlm.nih.gov/pubmed/30082730
http://dx.doi.org/10.1038/s41467-018-05589-4

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