Calcium is an essential cofactor for metal efflux by the ferroportin transporter family

Ferroportin (Fpn)—the only known cellular iron exporter—transports dietary and recycled iron into the blood plasma, and transfers iron across the placenta. Despite its central role in iron metabolism, our molecular understanding of Fpn-mediated iron efflux remains incomplete. Here, we report that Ca...

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Detalles Bibliográficos
Autores principales: Deshpande, Chandrika N., Ruwe, T. Alex, Shawki, Ali, Xin, Vicky, Vieth, Kyle R., Valore, Erika V., Qiao, Bo, Ganz, Tomas, Nemeth, Elizabeta, Mackenzie, Bryan, Jormakka, Mika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079014/
https://www.ncbi.nlm.nih.gov/pubmed/30082682
http://dx.doi.org/10.1038/s41467-018-05446-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079014/
https://www.ncbi.nlm.nih.gov/pubmed/30082682
http://dx.doi.org/10.1038/s41467-018-05446-4

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