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Calcium is an essential cofactor for metal efflux by the ferroportin transporter family
Ferroportin (Fpn)—the only known cellular iron exporter—transports dietary and recycled iron into the blood plasma, and transfers iron across the placenta. Despite its central role in iron metabolism, our molecular understanding of Fpn-mediated iron efflux remains incomplete. Here, we report that Ca...
Autores principales: | Deshpande, Chandrika N., Ruwe, T. Alex, Shawki, Ali, Xin, Vicky, Vieth, Kyle R., Valore, Erika V., Qiao, Bo, Ganz, Tomas, Nemeth, Elizabeta, Mackenzie, Bryan, Jormakka, Mika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079014/ https://www.ncbi.nlm.nih.gov/pubmed/30082682 http://dx.doi.org/10.1038/s41467-018-05446-4 |
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