MPP(+) decreases store-operated calcium entry and TRPC1 expression in Mesenchymal Stem Cell derived dopaminergic neurons

Parkinson’s disease is a neurodegenerative disorder involving the progressive loss of dopaminergic neurons (DNs), with currently available therapeutics, such as L-Dopa, only able to relieve some symptoms. Stem cell replacement is an attractive therapeutic option for PD patients, and DNs derived by d...

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Detalles Bibliográficos
Autores principales: Sun, Yuyang, Selvaraj, Senthil, Pandey, Sumali, Humphrey, Kristen M., Foster, James D., Wu, Min, Watt, John A., Singh, Brij B., Ohm, Joyce E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079049/
https://www.ncbi.nlm.nih.gov/pubmed/30082759
http://dx.doi.org/10.1038/s41598-018-29528-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079049/
https://www.ncbi.nlm.nih.gov/pubmed/30082759
http://dx.doi.org/10.1038/s41598-018-29528-x

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