Cbl-b deficiency provides protection against UVB-induced skin damage by modulating inflammatory gene signature

Exposure of skin to ultraviolet (UV) radiation induces DNA damage, inflammation, and immune suppression that ultimately lead to skin cancer. However, some of the pathways that regulate these events are poorly understood. We exposed mice to UVB to study its early effects in the absence of Cbl-b, a kn...

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Detalles Bibliográficos
Autores principales: Singh, Tej Pratap, Vieyra-Garcia, Pablo A., Wagner, Karin, Penninger, Josef, Wolf, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079082/
https://www.ncbi.nlm.nih.gov/pubmed/30082827
http://dx.doi.org/10.1038/s41419-018-0858-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079082/
https://www.ncbi.nlm.nih.gov/pubmed/30082827
http://dx.doi.org/10.1038/s41419-018-0858-5

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