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Cbl-b deficiency provides protection against UVB-induced skin damage by modulating inflammatory gene signature
Exposure of skin to ultraviolet (UV) radiation induces DNA damage, inflammation, and immune suppression that ultimately lead to skin cancer. However, some of the pathways that regulate these events are poorly understood. We exposed mice to UVB to study its early effects in the absence of Cbl-b, a kn...
Autores principales: | Singh, Tej Pratap, Vieyra-Garcia, Pablo A., Wagner, Karin, Penninger, Josef, Wolf, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079082/ https://www.ncbi.nlm.nih.gov/pubmed/30082827 http://dx.doi.org/10.1038/s41419-018-0858-5 |
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