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A novel probe to assess cytosolic entry of exogenous proteins

Dendritic cells use a specialized pathway called cross-presentation to activate CD8(+) T cells by presenting peptides from exogenous protein antigens on major histocompatibility complex class I molecules. Considerable evidence suggests that internalized antigens cross endocytic membranes to access c...

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Detalles Bibliográficos
Autores principales: Lu, Qiao, Grotzke, Jeff E., Cresswell, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079096/
https://www.ncbi.nlm.nih.gov/pubmed/30082832
http://dx.doi.org/10.1038/s41467-018-05556-z