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Tigecycline as a dual inhibitor of retinoblastoma and angiogenesis via inducing mitochondrial dysfunctions and oxidative damage

Retinoblastoma is the most common intraocular malignancy in children with poor prognosis. The progression of retinoblastoma is dependent on a robust angiogenic response. Targeting both retinoblastoma cells and angiogenesis may therefore provide an alternative therapeutic strategy in retinoblastoma....

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Detalles Bibliográficos
Autores principales: Xiong, Ying, Liu, Wei, Huang, Qian, Wang, Jierong, Wang, Yanjun, Li, Huijuan, Fu, Xuedong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079108/
https://www.ncbi.nlm.nih.gov/pubmed/30082885
http://dx.doi.org/10.1038/s41598-018-29938-x