Lico A Causes ER Stress and Apoptosis via Up-Regulating miR-144-3p in Human Lung Cancer Cell Line H292

During our study on the bioactivities of natural flavonoids, we found that the total flavonoids (TFs) and the main constituent of it, licochalcone A (lico A), activated unfolded protein response (UPR) and induced autophagy and thereby apoptosis in H292 cells. MicroRNAs, such as the tumor repressor m...

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Detalles Bibliográficos
Autores principales: Chen, Gang, Ma, Yueping, Jiang, Zhe, Feng, Yuan, Han, Yueqing, Tang, Yetian, Zhang, Juan, Ni, Hui, Li, Xuezheng, Li, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079201/
https://www.ncbi.nlm.nih.gov/pubmed/30108506
http://dx.doi.org/10.3389/fphar.2018.00837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079201/
https://www.ncbi.nlm.nih.gov/pubmed/30108506
http://dx.doi.org/10.3389/fphar.2018.00837

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