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Nucleotide Excision Repair Factor XPC Ameliorates Prognosis by Increasing the Susceptibility of Human Colorectal Cancer to Chemotherapy and Ionizing Radiation

Nucleotide excision repair (NER) is a DNA damage repair mechanism in mammals, but the relationship between NER and human colorectal cancer (HRC) progression has not been clarified yet. In this study, the expression of the NER genes XPA, XPC, XPF, XPG, ERCC1, and XPD was measured in normal and cancer...

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Detalles Bibliográficos
Autores principales: Hu, Liang-Bo, Chen, Yin, Meng, Xiao-Dong, Yu, Pan, He, Xu, Li, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079218/
https://www.ncbi.nlm.nih.gov/pubmed/30109214
http://dx.doi.org/10.3389/fonc.2018.00290