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Type M Resistance to Macrolides Is Due to a Two-Gene Efflux Transport System of the ATP-Binding Cassette (ABC) Superfamily

The mef(A) gene was originally identified as the resistance determinant responsible for type M resistance to macrolides, a phenotype frequently found in clinical isolates of Streptococcus pneumoniae and Streptococcus pyogenes. MefA was defined as a secondary transporter of the major facilitator supe...

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Detalles Bibliográficos
Autores principales: Iannelli, Francesco, Santoro, Francesco, Santagati, Maria, Docquier, Jean-Denis, Lazzeri, Elisa, Pastore, Gabiria, Cassone, Marco, Oggioni, Marco R., Rossolini, Gian M., Stefani, Stefania, Pozzi, Gianni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079230/
https://www.ncbi.nlm.nih.gov/pubmed/30108557
http://dx.doi.org/10.3389/fmicb.2018.01670