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Type M Resistance to Macrolides Is Due to a Two-Gene Efflux Transport System of the ATP-Binding Cassette (ABC) Superfamily
The mef(A) gene was originally identified as the resistance determinant responsible for type M resistance to macrolides, a phenotype frequently found in clinical isolates of Streptococcus pneumoniae and Streptococcus pyogenes. MefA was defined as a secondary transporter of the major facilitator supe...
Autores principales: | Iannelli, Francesco, Santoro, Francesco, Santagati, Maria, Docquier, Jean-Denis, Lazzeri, Elisa, Pastore, Gabiria, Cassone, Marco, Oggioni, Marco R., Rossolini, Gian M., Stefani, Stefania, Pozzi, Gianni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079230/ https://www.ncbi.nlm.nih.gov/pubmed/30108557 http://dx.doi.org/10.3389/fmicb.2018.01670 |
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