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Potential Roles of the Retinoblastoma Protein in Regulating Genome Editing
Genome editing is an important tool for modifying genomic DNA through introducing DNA insertion or deletion at specific locations of a genome. Recently CRISPR/Cas9 has been widely employed to improve the efficiency of genome editing. The Cas9 nuclease creates site-specific double strand breaks (DSBs...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079259/ https://www.ncbi.nlm.nih.gov/pubmed/30109230 http://dx.doi.org/10.3389/fcell.2018.00081 |