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Potential Roles of the Retinoblastoma Protein in Regulating Genome Editing

Genome editing is an important tool for modifying genomic DNA through introducing DNA insertion or deletion at specific locations of a genome. Recently CRISPR/Cas9 has been widely employed to improve the efficiency of genome editing. The Cas9 nuclease creates site-specific double strand breaks (DSBs...

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Detalles Bibliográficos
Autores principales: Jiang, Yuning, Chu, Wai Kit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079259/
https://www.ncbi.nlm.nih.gov/pubmed/30109230
http://dx.doi.org/10.3389/fcell.2018.00081