Parameter Optimization Using Covariance Matrix Adaptation—Evolutionary Strategy (CMA-ES), an Approach to Investigate Differences in Channel Properties Between Neuron Subtypes

Computational models in neuroscience can be used to predict causal relationships between biological mechanisms in neurons and networks, such as the effect of blocking an ion channel or synaptic connection on neuron activity. Since developing a biophysically realistic, single neuron model is exceedin...

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Detalles Bibliográficos
Autores principales: Jȩdrzejewski-Szmek, Zbigniew, Abrahao, Karina P., Jȩdrzejewska-Szmek, Joanna, Lovinger, David M., Blackwell, Kim T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079282/
https://www.ncbi.nlm.nih.gov/pubmed/30108495
http://dx.doi.org/10.3389/fninf.2018.00047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079282/
https://www.ncbi.nlm.nih.gov/pubmed/30108495
http://dx.doi.org/10.3389/fninf.2018.00047

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