Efficient Non-viral Gene Delivery into Human Hematopoietic Stem Cells by Minicircle Sleeping Beauty Transposon Vectors

The Sleeping Beauty (SB) transposon system is a non-viral gene delivery platform that combines simplicity, inexpensive manufacture, and favorable safety features in the context of human applications. However, efficient correction of hematopoietic stem and progenitor cells (HSPCs) with non-viral vect...

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Detalles Bibliográficos
Autores principales: Holstein, Marta, Mesa-Nuñez, Cristina, Miskey, Csaba, Almarza, Elena, Poletti, Valentina, Schmeer, Marco, Grueso, Esther, Ordóñez Flores, Juan Carlos, Kobelt, Dennis, Walther, Wolfgang, Aneja, Manish K., Geiger, Johannes, Bonig, Halvard B., Izsvák, Zsuzsanna, Schleef, Martin, Rudolph, Carsten, Mavilio, Fulvio, Bueren, Juan A., Guenechea, Guillermo, Ivics, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079369/
https://www.ncbi.nlm.nih.gov/pubmed/29503198
http://dx.doi.org/10.1016/j.ymthe.2018.01.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079369/
https://www.ncbi.nlm.nih.gov/pubmed/29503198
http://dx.doi.org/10.1016/j.ymthe.2018.01.012

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