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Thymosin β4 Prevents Oxidative Stress, Inflammation, and Fibrosis in Ethanol- and LPS-Induced Liver Injury in Mice

Thymosin beta 4 (Tβ4), an actin-sequestering protein, is involved in tissue development and regeneration. It prevents inflammation and fibrosis in several tissues. We investigated the role of Tβ4 in chronic ethanol- and acute lipopolysaccharide- (LPS-) induced mouse liver injury. C57BL/6 mice were f...

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Detalles Bibliográficos
Autores principales: Shah, Ruchi, Reyes-Gordillo, Karina, Cheng, Ying, Varatharajalu, Ravi, Ibrahim, Joseph, Lakshman, M. Raj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079392/
https://www.ncbi.nlm.nih.gov/pubmed/30116499
http://dx.doi.org/10.1155/2018/9630175