Cargando…

Thymosin β4 Prevents Oxidative Stress, Inflammation, and Fibrosis in Ethanol- and LPS-Induced Liver Injury in Mice

Thymosin beta 4 (Tβ4), an actin-sequestering protein, is involved in tissue development and regeneration. It prevents inflammation and fibrosis in several tissues. We investigated the role of Tβ4 in chronic ethanol- and acute lipopolysaccharide- (LPS-) induced mouse liver injury. C57BL/6 mice were f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shah, Ruchi, Reyes-Gordillo, Karina, Cheng, Ying, Varatharajalu, Ravi, Ibrahim, Joseph, Lakshman, M. Raj
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079392/ https://www.ncbi.nlm.nih.gov/pubmed/30116499 http://dx.doi.org/10.1155/2018/9630175

Ejemplares similares

Low-ω3 Fatty Acid and Soy Protein Attenuate Alcohol-Induced Fatty Liver and Injury by Regulating the Opposing Lipid Oxidation and Lipogenic Signaling Pathways
por: Reyes-Gordillo, Karina, et al.
Publicado: (2016)

Protective Role of Dietary Curcumin in the Prevention of the Oxidative Stress Induced by Chronic Alcohol with respect to Hepatic Injury and Antiatherogenic Markers
por: Varatharajalu, Ravi, et al.
Publicado: (2016)

Akt1 and Akt2 Isoforms Play Distinct Roles in Regulating the Development of Inflammation and Fibrosis Associated with Alcoholic Liver Disease
por: Reyes-Gordillo, Karina, et al.
Publicado: (2019)

Oxidative Stress and Inflammation in Hepatic Diseases: Current and Future Therapy
por: Reyes-Gordillo, Karina, et al.
Publicado: (2017)

Potential Role of Thymosin Beta 4 in Liver Fibrosis
por: Kim, Jieun, et al.
Publicado: (2015)

Effects of exogenous thymosin β4 on carbon tetrachloride-induced liver injury and fibrosis
por: Li, Xiankui, et al.
Publicado: (2017)

Protection effect of thymosin β4 on ethanol injury in corneal stromal keratocyte
por: Liu, Jinghua, et al.
Publicado: (2022)

Spermidine Prevents Ethanol and Lipopolysaccharide-Induced Hepatic Injury in Mice
por: Adhikari, Raghabendra, et al.
Publicado: (2021)

Identification of Thymosin β4 as an effector of Hand1-mediated vascular development
por: Smart, Nicola, et al.
Publicado: (2010)

β-Thymosins and Hemocyte Homeostasis in a Crustacean
por: Saelee, Netnapa, et al.
Publicado: (2013)

Progress on the Function and Application of Thymosin β4
por: Xing, Yuan, et al.
Publicado: (2021)

Thymosin β4 and its degradation product, Ac-SDKP, are novel reparative factors in renal fibrosis
por: Zuo, Yiqin, et al.
Publicado: (2013)

Thymosin β4 Protects against Cardiac Damage and Subsequent Cardiac Fibrosis in Mice with Myocardial Infarction
por: Wang, Fei, et al.
Publicado: (2022)

Thymosin β4 Improves Differentiation and Vascularization of EHTs
por: Ziegler, Tilman, et al.
Publicado: (2017)

The Pathophysiological Role of Thymosin β4 in the Kidney Glomerulus
por: Mason, William J., et al.
Publicado: (2023)

Thymosin beta4 sylphoxide: potential role in resolution of inflammation?
por: Young, JD, et al.
Publicado: (2001)

Thymosin Beta 4 and Thymosin Beta 10 Expression in Hepatocellular Carcinoma
por: Theunissen, W., et al.
Publicado: (2014)

The expression of thymosin β4 in chronic hepatitis B combined nonalcoholic fatty liver disease
por: Liang, Jing, et al.
Publicado: (2016)

Loss of endogenous thymosin β(4) accelerates glomerular disease
por: Vasilopoulou, Elisavet, et al.
Publicado: (2016)

Multiple fuzzy interactions in the moonlighting function of thymosin-β4
por: Tantos, Agnes, et al.
Publicado: (2013)

Ethosomal Gel for Improving Transdermal Delivery of Thymosin β-4
por: Fu, Xianglei, et al.
Publicado: (2019)

Thymosin β4 dynamics during chicken enteroid development
por: Acharya, Mohan, et al.
Publicado: (2020)

Effects of Thymosin β4 on Myocardial Apoptosis in Burned Rats
por: Wu, Xiaoming, et al.
Publicado: (2022)

Thymosin β4 alleviates renal fibrosis and tubular cell apoptosis through TGF-β pathway inhibition in UUO rat models
por: Yuan, Jing, et al.
Publicado: (2017)

Expression pattern of thymosin beta 4 in the adult human liver
por: Nemolato, S., et al.
Publicado: (2011)

Preventive and therapeutic effects of thymosin β4 N-terminal fragment Ac-SDKP in the bleomycin model of pulmonary fibrosis
por: Conte, Enrico, et al.
Publicado: (2016)

Targeted Deletion of Thymosin Beta 4 in Hepatic Stellate Cells Ameliorates Liver Fibrosis in a Transgenic Mouse Model
por: Kim, Jieun, et al.
Publicado: (2023)

Thymosin α1 treatment reduces hepatic inflammation and inhibits hepatocyte apoptosis in rats with acute liver failure
por: Yang, Xueliang, et al.
Publicado: (2018)

Thymosin Beta 4 Inhibits LPS and ATP-Induced Hepatic Stellate Cells via the Regulation of Multiple Signaling Pathways
por: Choi, Jihye, et al.
Publicado: (2023)

Pyrus ussuriensis Maxim 70% ethanol eluted fraction ameliorates inflammation and oxidative stress in LPS‐induced inflammation in vitro and in vivo
por: Peng, Fei, et al.
Publicado: (2022)

Suppression of thymosin β10 increases cell migration and metastasis of cholangiocarcinoma
por: Sribenja, Sirinapa, et al.
Publicado: (2013)

Thymosin β 10 is overexpressed and associated with unfavorable prognosis in hepatocellular carcinoma
por: Song, Chunrong, et al.
Publicado: (2019)

Thymosin β4 Is an Endogenous Iron Chelator and Molecular Switcher of Ferroptosis
por: Lachowicz, Joanna I., et al.
Publicado: (2022)

Aberrant developmental titin splicing and dysregulated sarcomere length in Thymosin β4 knockout mice
por: Smart, Nicola, et al.
Publicado: (2017)

Thymosin β4-sulfoxide attenuates inflammatory cell infiltration and promotes cardiac wound healing
por: Evans, Mark A., et al.
Publicado: (2013)

Thymosin β4 protects against aortic aneurysm via endocytic regulation of growth factor signaling
por: Munshaw, Sonali, et al.
Publicado: (2021)

Immunoreactivity for Thymosin Beta 4 and Thymosin Beta 10 in the Adult Rat Oro-Gastro-Intestinal tract
por: Nemolato, S, et al.
Publicado: (2013)

Association of serum thymosin β4 with malnutrition-inflammation-atherosclerosis syndrome in peritoneal dialysis patients: a cross-sectional study
por: Tian, Jiakun, et al.
Publicado: (2023)

Thymosin β4 coated nanofiber scaffolds for the repair of damaged cardiac tissue
por: Kumar, Arun, et al.
Publicado: (2014)

Effect of vitamin A deficiency on thymosin-β4 and CD4 concentrations
por: El-Zayat, Salwa Refat, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_clqht2b5ciddkrs1t7f0r3ddhp