Knockdown of Sestrin2 Increases Lipopolysaccharide-Induced Oxidative Stress, Apoptosis, and Fibrotic Reactions in H9c2 Cells and Heart Tissues of Mice via an AMPK-Dependent Mechanism

Sestrin2 (sesn2) is an endogenous antioxidant protein that has recently gained attention for its potential to treat various inflammatory diseases. However, the relationship of sesn2 with cardiomyopathy is still unclear. In H9c2 cells, sesn2 knockdown reduced the level of 5′ adenosine monophosphate-a...

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Detalles Bibliográficos
Autores principales: Hwang, Hwan-Jin, Kim, Joo Won, Chung, Hye Soo, Seo, Ji A., Kim, Sin Gon, Kim, Nan Hee, Choi, Kyung Mook, Baik, Sei Hyun, Yoo, Hye Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079459/
https://www.ncbi.nlm.nih.gov/pubmed/30116150
http://dx.doi.org/10.1155/2018/6209140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079459/
https://www.ncbi.nlm.nih.gov/pubmed/30116150
http://dx.doi.org/10.1155/2018/6209140

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