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Dipeptidyl-Peptidase 4 Inhibitor Sitagliptin Ameliorates Hepatic Insulin Resistance by Modulating Inflammation and Autophagy in ob/ob Mice

Obesity and type 2 diabetes are the most common metabolic diseases globally. They are associated with inflammation, oxidative stress, autophagy, and insulin resistance. Sitagliptin, a dipeptidyl-peptidase 4 inhibitor, has been reported to show multiple biological activities beyond the antidiabetic p...

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Detalles Bibliográficos
Autores principales: Zheng, Wenbin, Zhou, Jing, Song, Shasha, Kong, Wen, Xia, Wenfang, Chen, Lulu, Zeng, Tianshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079465/
https://www.ncbi.nlm.nih.gov/pubmed/30123267
http://dx.doi.org/10.1155/2018/8309723