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Therapeutic effect of Sirtuin 3 on ameliorating nonalcoholic fatty liver disease: The role of the ERK-CREB pathway and Bnip3-mediated mitophagy

Increased mitochondrial damage is related to the progression of a diet-induced nonalcoholic fatty liver disease. The aim of our study is to investigate the role of Sirtuin 3 (Sirt3) in treating nonalcoholic fatty liver disease with a focus on mitophagy and the ERK-CREB pathway. Our data indicated th...

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Detalles Bibliográficos
Autores principales: Li, Ruibing, Xin, Ting, Li, Dandan, Wang, Chengbin, Zhu, Hang, Zhou, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079484/
https://www.ncbi.nlm.nih.gov/pubmed/30056271
http://dx.doi.org/10.1016/j.redox.2018.07.011