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Epac1 Restores Normal Insulin Signaling through a Reduction in Inflammatory Cytokines

We have previously reported that Epac1 reduced inflammatory cytokines, which is protective to the diabetic retina. We have also published that impaired insulin signaling occurs in the diabetic retina. A reduction in interleukin-1 beta (IL-1β) and tumor necrosis factor alpha (TNFα) by Epac1 could pot...

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Detalles Bibliográficos
Autores principales: Curtiss, Elizabeth, Jiang, Youde, Liu, Li, Hawthorne, Claire, Zhang, Jessica, Steinle, Jena J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079497/
https://www.ncbi.nlm.nih.gov/pubmed/30116147
http://dx.doi.org/10.1155/2018/3809092