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Deficiency in intestinal epithelial O‐GlcNAcylation predisposes to gut inflammation

Post‐translational modifications in intestinal epithelial cells (IECs) allow for precise control in intestinal homeostasis, the breakdown of which may precipitate the pathological damage and inflammation in inflammatory bowel disease. The O‐linked β‐N‐acetylglucosamine (O‐GlcNAc) modification on int...

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Detalles Bibliográficos
Autores principales: Zhao, Ming, Xiong, Xiwen, Ren, Kaiqun, Xu, Bing, Cheng, Meng, Sahu, Chinmayi, Wu, Kaichun, Nie, Yongzhan, Huang, Zan, Blumberg, Richard S, Han, Xiaonan, Ruan, Hai‐Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079539/
https://www.ncbi.nlm.nih.gov/pubmed/29941542
http://dx.doi.org/10.15252/emmm.201708736