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AAV‐mediated gene therapy as a strategy to fight obesity and metabolic diseases

The fibroblast growth factor 21 (FGF21) is a member of the FGF superfamily that now comprises 22 members identified in humans. Unlike the canonical role of most FGF family members, FGF21 is released into the circulation and acts as an endocrine hormone by binding with low affinity to FGF receptors (...

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Detalles Bibliográficos
Autores principales: Sponton, Carlos Henrique, Kajimura, Shingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079540/
https://www.ncbi.nlm.nih.gov/pubmed/30021799
http://dx.doi.org/10.15252/emmm.201809431