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Systemic Alterations of Wnt Inhibitors in Patients with Prostate Cancer and Bone Metastases

PURPOSE: Dickkopf-1 (DKK-1) and sclerostin seem to inhibit osteoblast activity by blocking the Wnt pathway, which leads to progression of metastatic prostate cancer (PC). However, it is unknown whether serum levels of these proteins are altered in PC patients with or without metastasis. The aim of t...

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Detalles Bibliográficos
Autores principales: Aufderklamm, Stefan, Hennenlotter, Jörg, Leidenberger, Phillip, Rausch, Steffen, Hohneder, Andrea, Kühs, Ursula, Maas, Moritz, Schwentner, Christian, Bedke, Jens, Stenzl, Arnulf, Todenhöfer, Tilman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079590/
https://www.ncbi.nlm.nih.gov/pubmed/30116403
http://dx.doi.org/10.1155/2018/1874598