Experimental intravascular hemolysis induces hemodynamic and pathological pulmonary hypertension: association with accelerated purine metabolism

Pulmonary hypertension (PH) is emerging as a serious complication associated with hemolytic disorders, and plexiform lesions (PXL) have been reported in patients with sickle cell disease (SCD). We hypothesized that repetitive hemolysis per se induces PH and angioproliferative vasculopathy and evalua...

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Detalles Bibliográficos
Autores principales: Bilan, Victor P., Schneider, Frank, Novelli, Enrico M., Kelley, Eric E., Shiva, Sruti, Gladwin, Mark T., Jackson, Edwin K., Tofovic, Stevan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080084/
https://www.ncbi.nlm.nih.gov/pubmed/30003836
http://dx.doi.org/10.1177/2045894018791557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080084/
https://www.ncbi.nlm.nih.gov/pubmed/30003836
http://dx.doi.org/10.1177/2045894018791557

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