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QSAR Modeling of Histamine H(3)R Antagonists/inverse Agonists as Future Drugs for Neurodegenerative Diseases

BACKGROUND: Histamine H(3) receptor (H(3)R) is associated with several neuropsychological diseases, and thus it is an important target involved in several CNS disorders, such as narcolepsy, attention deficit hyperactivity disorder and schizophrenia. Since QSAR modeling is a feasible approach to expl...

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Detalles Bibliográficos
Autores principales: Corrêa, Michelle Fidelis, Fernandes, João Paulo dos Santos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080103/
https://www.ncbi.nlm.nih.gov/pubmed/28820054
http://dx.doi.org/10.2174/1570159X15666170818100644