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Fisetin Inhibited Growth and Metastasis of Triple-Negative Breast Cancer by Reversing Epithelial-to-Mesenchymal Transition via PTEN/Akt/GSK3β Signal Pathway

Triple negative breast cancer (TNBC), characterized by its highly aggressive and metastatic features, is associated with poor prognosis and high mortality partly due to lack of effective treatment. Fisetin, a natural flavonoid compound, has been demonstrated to possess anti-cancer effects in various...

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Detalles Bibliográficos
Autores principales: Li, Jie, Gong, Xia, Jiang, Rong, Lin, Dan, Zhou, Tao, Zhang, Aijie, Li, Hongzhong, Zhang, Xiang, Wan, Jingyuan, Kuang, Ge, Li, Hongyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080104/
https://www.ncbi.nlm.nih.gov/pubmed/30108501
http://dx.doi.org/10.3389/fphar.2018.00772