Cargando…

Fisetin Inhibited Growth and Metastasis of Triple-Negative Breast Cancer by Reversing Epithelial-to-Mesenchymal Transition via PTEN/Akt/GSK3β Signal Pathway

Triple negative breast cancer (TNBC), characterized by its highly aggressive and metastatic features, is associated with poor prognosis and high mortality partly due to lack of effective treatment. Fisetin, a natural flavonoid compound, has been demonstrated to possess anti-cancer effects in various...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Jie, Gong, Xia, Jiang, Rong, Lin, Dan, Zhou, Tao, Zhang, Aijie, Li, Hongzhong, Zhang, Xiang, Wan, Jingyuan, Kuang, Ge, Li, Hongyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080104/ https://www.ncbi.nlm.nih.gov/pubmed/30108501 http://dx.doi.org/10.3389/fphar.2018.00772

Ejemplares similares

Biejiajian Pill Inhibits Carcinogenesis and Metastasis via the Akt/GSK-3β/Snail Signaling Pathway in Hepatocellular Carcinoma
por: Sun, Jialing, et al.
Publicado: (2021)

Fisetin Prevents Acetaminophen-Induced Liver Injury by Promoting Autophagy
por: Zhang, Jiaqi, et al.
Publicado: (2020)

β-Sitosterol and Gemcitabine Exhibit Synergistic Anti-pancreatic Cancer Activity by Modulating Apoptosis and Inhibiting Epithelial–Mesenchymal Transition by Deactivating Akt/GSK-3β Signaling
por: Cao, Zhang-qi, et al.
Publicado: (2019)

Fisetin Attenuates Diabetic Nephropathy-Induced Podocyte Injury by Inhibiting NLRP3 Inflammasome
por: Dong, Wenmin, et al.
Publicado: (2022)

Corrigendum: β-Sitosterol and Gemcitabine Exhibit Synergistic Anti-Pancreatic Cancer Activity by Modulating Apoptosis and Inhibiting Epithelial–Mesenchymal Transition by Deactivating Akt/GSK-3β Signaling
por: Cao, Zhang-qi, et al.
Publicado: (2020)

Fisetin Alleviated Bleomycin-Induced Pulmonary Fibrosis Partly by Rescuing Alveolar Epithelial Cells From Senescence
por: Zhang, Li, et al.
Publicado: (2020)

Fisetin: An Integrated Approach to Identify a Strategy Promoting Osteogenesis
por: Dalle Carbonare, Luca, et al.
Publicado: (2022)

Modified Sijunzi Decoction Inhibits Epithelial-Mesenchymal Transition of Non-Small Cell Lung Cancer by Attenuating AKT/GSK3β Pathway in vitro and in vivo
por: Shao, Niu, et al.
Publicado: (2022)

Traditional Chinese Medicines as Effective Reversals of Epithelial-Mesenchymal Transition Induced-Metastasis of Colorectal Cancer: Molecular Targets and Mechanisms
por: Ge, Hongzhang, et al.
Publicado: (2022)

Resveratrol inhibits the invasion and metastasis of colon cancer through reversal of epithelial- mesenchymal transition via the AKT/GSK-3β/Snail signaling pathway
por: Yuan, Li, et al.
Publicado: (2019)

Resveratrol inhibits the invasion and metastasis of colon cancer through reversal of epithelial-mesenchymal transition via the AKT/GSK-3β/Snail signaling pathway
por: Yuan, Li, et al.
Publicado: (2022)

Jiedu Sangen Decoction Reverses Epithelial-to-mesenchymal Transition and Inhibits Invasion and Metastasis of Colon Cancer via AKT/GSK-3β Signaling Pathway
por: Yuan, Li, et al.
Publicado: (2019)

Fisetin Attenuates Doxorubicin-Induced Cardiomyopathy In Vivo and In Vitro by Inhibiting Ferroptosis Through SIRT1/Nrf2 Signaling Pathway Activation
por: Li, Danlei, et al.
Publicado: (2022)

The neuroprotective effects of fisetin, a natural flavonoid in neurodegenerative diseases: Focus on the role of oxidative stress
por: Hassan, Syed Shams ul, et al.
Publicado: (2022)

Jiedu Sangen Decoction Reverses Epithelial-to-mesenchymal Transition and Inhibits Invasion and Metastasis of Colon Cancer via AKT/GSK-3β Signaling Pathway: Erratum
por: Yuan, Li, et al.
Publicado: (2022)

Water extract of cacumen platycladi promotes hair growth through the Akt/GSK3β/β-catenin signaling pathway
por: Fu, Hangjie, et al.
Publicado: (2023)

Resveratrol Attenuates High Glucose-Induced Osteoblast Dysfunction via AKT/GSK3β/FYN-Mediated NRF2 Activation
por: Xuan, Yue, et al.
Publicado: (2022)

Arctigenin Attenuates Tumor Metastasis Through Inhibiting Epithelial–Mesenchymal Transition in Hepatocellular Carcinoma via Suppressing GSK3β-Dependent Wnt/β-Catenin Signaling Pathway In Vivo and In Vitro
por: Lu, Zheng, et al.
Publicado: (2019)

Sodium Dichloroacetate Stimulates Angiogenesis by Improving Endothelial Precursor Cell Function in an AKT/GSK-3β/Nrf2 Dependent Pathway in Vascular Dementia Rats
por: Zhao, Hui, et al.
Publicado: (2019)

Corrigendum: Water extract of cacumen platycladi promotes hair growth through the Akt/GSK3β/β-catenin signaling pathway
por: Fu, Hangjie, et al.
Publicado: (2023)

Fisetin Rescues the Mice Brains Against D-Galactose-Induced Oxidative Stress, Neuroinflammation and Memory Impairment
por: Ahmad, Sareer, et al.
Publicado: (2021)

Corrigendum: The neuroprotective effects of fisetin, a natural flavonoid in neurodegenerative diseases: Focus on the role of oxidative stress
por: Hassan, Syed Shams ul, et al.
Publicado: (2022)

Astragaloside IV Alleviates Intestinal Barrier Dysfunction via the AKT-GSK3β-β-Catenin Pathway in Peritoneal Dialysis
por: He, Jiaqi, et al.
Publicado: (2022)

SCD1 Confers Temozolomide Resistance to Human Glioma Cells via the Akt/GSK3β/β-Catenin Signaling Axis
por: Dai, Shuang, et al.
Publicado: (2018)

Fisetin Attenuates Myocardial Ischemia-Reperfusion Injury by Activating the Reperfusion Injury Salvage Kinase (RISK) Signaling Pathway
por: Shanmugam, Karthi, et al.
Publicado: (2021)

Corrigendum: SCD1 Confers Temozolomide Resistance to Human Glioma Cells Via the Akt/GSK3β/β-Catenin Signaling Axis
por: Dai, Shuang, et al.
Publicado: (2019)

Paeoniflorin Inhibits Mesangial Cell Proliferation and Inflammatory Response in Rats With Mesangial Proliferative Glomerulonephritis Through PI3K/AKT/GSK-3β Pathway
por: Liu, Bihao, et al.
Publicado: (2019)

Bone marrow mesenchymal stem cell-derived small extracellular vesicles promote liver regeneration via miR-20a-5p/PTEN
por: Zhang, Jing, et al.
Publicado: (2023)

Exosome CTLA-4 Regulates PTEN/CD44 Signal Pathway in Spleen Deficiency Internal Environment to Promote Invasion and Metastasis of Hepatocellular Carcinoma
por: Wang, Yongdan, et al.
Publicado: (2021)

Integrating network pharmacology prediction and experimental investigation to verify ginkgetin anti-invasion and metastasis of human lung adenocarcinoma cells via the Akt/GSK-3β/Snail and Wnt/β-catenin pathway
por: Liu, Kaile, et al.
Publicado: (2023)

Dec1 Deficiency Ameliorates Pulmonary Fibrosis Through the PI3K/AKT/GSK-3β/β-Catenin Integrated Signaling Pathway
por: Hu, Xingxing, et al.
Publicado: (2022)

MicroRNA-216a promotes the metastasis and epithelial–mesenchymal transition of ovarian cancer by suppressing the PTEN/AKT pathway
por: Liu, Haizhi, et al.
Publicado: (2017)

Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/Akt signaling pathway in gastric cancer
por: Xu, Jiahui, et al.
Publicado: (2017)

Estradiol Activates PI3K/Akt/GSK3 Pathway Under Chronic Neurodegenerative Conditions Triggered by Perinatal Asphyxia
por: Saraceno, G. Ezequiel, et al.
Publicado: (2018)

Cariporide Attenuates Doxorubicin-Induced Cardiotoxicity in Rats by Inhibiting Oxidative Stress, Inflammation and Apoptosis Partly Through Regulation of Akt/GSK-3β and Sirt1 Signaling Pathway
por: Liao, Wenli, et al.
Publicado: (2022)

Ethanol Extract of Brucea javanica Seed Inhibit Triple-Negative Breast Cancer by Restraining Autophagy via PI3K/Akt/mTOR Pathway
por: Chen, Xiaohong, et al.
Publicado: (2020)

Isoorientin Ameliorates APAP-Induced Hepatotoxicity via Activation Nrf2 Antioxidative Pathway: The Involvement of AMPK/Akt/GSK3β
por: Fan, Xiaoye, et al.
Publicado: (2018)

SQLE Knockdown inhibits bladder cancer progression by regulating the PTEN/AKT/GSK3β signaling pathway through P53
por: Zou, Fan, et al.
Publicado: (2023)

Effect of Fushengong Decoction on PTEN/PI3K/AKT/NF-κB Pathway in Rats With Chronic Renal Failure via Dual-Dimension Network Pharmacology Strategy
por: Luo, Hongyu, et al.
Publicado: (2022)

Correction: Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/ Akt signaling pathway in gastric cancer
por: Xu, Jiahui, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_s86ok7vq9sov548locqcbof3nu