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MIS416 as a siRNA Delivery System with the Ability to Target Antigen-Presenting Cells

MIS416 is a microparticulate formulation derived from propionibacterium acnes cell wall skeletons with intrinsic adjuvant activity. Conjugates of MIS416-SS-peptide containing a disulfide linkage facilitate the cytoplasmic delivery and release of peptides in antigen-presenting cells (APCs). We hypoth...

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Detalles Bibliográficos
Autores principales: Mainini, Francesco, Larsen, David S., Webster, Gill A., Young, Sarah L., Eccles, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080116/
https://www.ncbi.nlm.nih.gov/pubmed/29893623
http://dx.doi.org/10.1089/nat.2017.0695