Cargando…
MIS416 as a siRNA Delivery System with the Ability to Target Antigen-Presenting Cells
MIS416 is a microparticulate formulation derived from propionibacterium acnes cell wall skeletons with intrinsic adjuvant activity. Conjugates of MIS416-SS-peptide containing a disulfide linkage facilitate the cytoplasmic delivery and release of peptides in antigen-presenting cells (APCs). We hypoth...
Autores principales: | Mainini, Francesco, Larsen, David S., Webster, Gill A., Young, Sarah L., Eccles, Michael R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080116/ https://www.ncbi.nlm.nih.gov/pubmed/29893623 http://dx.doi.org/10.1089/nat.2017.0695 |
Ejemplares similares
-
Bridging Small Molecules to Modified Bacterial Microparticles Using a Disulphide Linkage: MIS416 as a Cargo Delivery System
por: Mainini, Francesco, et al.
Publicado: (2015) -
Lipid and Polymer-Based Nanoparticle siRNA Delivery Systems for Cancer Therapy
por: Mainini, Francesco, et al.
Publicado: (2020) -
Targeted delivery of ZNF416 siRNA-loaded liposomes attenuates experimental pulmonary fibrosis
por: Cheng, Demin, et al.
Publicado: (2022) -
Safety, tolerability and pharmacodynamics of a novel immunomodulator, MIS416, in patients with chronic progressive multiple sclerosis
por: Luckey, Alison M, et al.
Publicado: (2015) -
Targeting Innate Receptors with MIS416 Reshapes Th Responses and Suppresses CNS Disease in a Mouse Model of Multiple Sclerosis
por: White, Madeleine, et al.
Publicado: (2014)