Sertoli Cells Engineered to Express Insulin to Lower Blood Glucose in Diabetic Mice

Long-term survival of allo- and xenotransplanted immune-privileged Sertoli cells (SCs) is well documented suggesting that SCs can be used to deliver foreign proteins for cell-based gene therapy. The aim of this study was to use a lentivirus carrying proinsulin cDNA to achieve stable expression and l...

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Detalles Bibliográficos
Autores principales: Kaur, Gurvinder, Thompson, Lea Ann, Babcock, Rachel L., Mueller, Karl, Dufour, Jannette M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2018
Materias:
Molecular Mechanisms of Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080125/
https://www.ncbi.nlm.nih.gov/pubmed/29927618
http://dx.doi.org/10.1089/dna.2017.3937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080125/
https://www.ncbi.nlm.nih.gov/pubmed/29927618
http://dx.doi.org/10.1089/dna.2017.3937

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