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Neutrophil elastase inhibition effectively rescued angiopoietin-1 decrease and inhibits glial scar after spinal cord injury

After spinal cord injury (SCI), neutrophil elastase (NE) released at injury site disrupts vascular endothelium integrity and stabilization. Angiopoietins (ANGPTs) are vascular growth factors that play an important role in vascular stabilization. We hypothesized that neutrophil elastase is one of the...

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Detalles Bibliográficos
Autores principales: Kumar, Hemant, Choi, Hyemin, Jo, Min-Jae, Joshi, Hari Prasad, Muttigi, Manjunatha, Bonanomi, Dario, Kim, Sung Bum, Ban, Eunmi, Kim, Aeri, Lee, Soo-Hong, Kim, Kyoung-Tae, Sohn, Seil, Zeng, Xiang, Han, Inbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080383/
https://www.ncbi.nlm.nih.gov/pubmed/30086801
http://dx.doi.org/10.1186/s40478-018-0576-3