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Influence of the KCNQ1 S140G Mutation on Human Ventricular Arrhythmogenesis and Pumping Performance: Simulation Study

The KCNQ1 S140G mutation, which is involved in I(Ks) current, affects atrial fibrillation. However, little is known about its effect on the mechanical behavior of the heart. Therefore, we assessed the influence of the KCNQ1 S140G mutation on ventricular electrophysiological stability and mechanical...

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Detalles Bibliográficos
Autores principales: Jeong, Da Un, Lim, Ki Moo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080549/
https://www.ncbi.nlm.nih.gov/pubmed/30108508
http://dx.doi.org/10.3389/fphys.2018.00926