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Immune Cell Hacking: Challenges and Clinical Approaches to Create Smarter Generations of Chimeric Antigen Receptor T Cells

T cells equipped with chimeric antigen receptors (CAR T cells) have recently provided promising advances as a novel immunotherapeutic approach for cancer treatment. CAR T cell therapy has shown stunning results especially in B-cell malignancies; however, it has shown less success against solid tumor...

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Detalles Bibliográficos
Autores principales: Elahi, Reza, Khosh, Elnaz, Tahmasebi, Safa, Esmaeilzadeh, Abdolreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080612/
https://www.ncbi.nlm.nih.gov/pubmed/30108584
http://dx.doi.org/10.3389/fimmu.2018.01717