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Clinical, Pathological, and Molecular Characteristics of CpG Island Methylator Phenotype in Colorectal Cancer: A Systematic Review and Meta-analysis

BACKGROUND: CpG island methylator phenotype (CIMP) tumors, comprising 20% of colorectal cancers, are associated with female sex, age, right-sided location, and BRAF mutations. However, other factors potentially associated with CIMP have not been robustly examined. This meta-analysis provides a compr...

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Detalles Bibliográficos
Autores principales: Advani, Shailesh M., Advani, Pragati, DeSantis, Stacia M., Brown, Derek, VonVille, Helena M., Lam, Michael, Loree, Jonathan M., Sarshekeh, Amir Mehrvarz, Bressler, Jan, Lopez, David S., Daniel, Carrie R., Swartz, Michael D., Kopetz, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080640/
https://www.ncbi.nlm.nih.gov/pubmed/30071442
http://dx.doi.org/10.1016/j.tranon.2018.07.008