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ARL2BP, a protein linked to retinitis pigmentosa, is needed for normal photoreceptor cilia doublets and outer segment structure

The outer segment (OS) of photoreceptor cells is an elaboration of a primary cilium with organized stacks of membranous disks that contain the proteins needed for phototransduction and vision. Though ciliary formation and function has been well characterized, little is known about the role of cilia...

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Detalles Bibliográficos
Autores principales: Moye, Abigail R., Singh, Ratnesh, Kimler, Victoria A., Dilan, Tanya L., Munezero, Daniella, Saravanan, Thamaraiselvi, Goldberg, Andrew F. X., Ramamurthy, Visvanathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080659/
https://www.ncbi.nlm.nih.gov/pubmed/29718757
http://dx.doi.org/10.1091/mbc.E18-01-0040