Synthesis of a hemin-containing copolymer as a novel immunostimulator that induces IFN-gamma production

BACKGROUND: Hemozoin, a chemical analog of a malarial pigment, is a crystal composed of heme dimers that can act as a potent Th1-type adjuvant, which strongly induces antibody production. However, the clinical applications of malarial hemozoin have limitations due to biosafety concerns and difficult...

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Detalles Bibliográficos
Autores principales: Hoshi, Kazuaki, Yamazaki, Tomohiko, Yoshikawa, Chiaki, Tsugawa, Wakako, Ikebukuro, Kazunori, Sode, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080671/
https://www.ncbi.nlm.nih.gov/pubmed/30122920
http://dx.doi.org/10.2147/IJN.S166259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080671/
https://www.ncbi.nlm.nih.gov/pubmed/30122920
http://dx.doi.org/10.2147/IJN.S166259

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