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Synthesis of a hemin-containing copolymer as a novel immunostimulator that induces IFN-gamma production
BACKGROUND: Hemozoin, a chemical analog of a malarial pigment, is a crystal composed of heme dimers that can act as a potent Th1-type adjuvant, which strongly induces antibody production. However, the clinical applications of malarial hemozoin have limitations due to biosafety concerns and difficult...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080671/ https://www.ncbi.nlm.nih.gov/pubmed/30122920 http://dx.doi.org/10.2147/IJN.S166259 |