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Subcellular topography modulates actin dynamics and signaling in B-cells

B-cell signaling activation is most effectively triggered by the binding of B-cell receptors (BCRs) to membrane-bound antigens. In vivo, B-cells encounter antigen on antigen-presenting cells (APC), which possess complex surfaces with convoluted topographies, a fluid membrane and deformable cell bodi...

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Detalles Bibliográficos
Autores principales: Ketchum, Christina M., Sun, Xiaoyu, Suberi, Alexandra, Fourkas, John T., Song, Wenxia, Upadhyaya, Arpita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080708/
https://www.ncbi.nlm.nih.gov/pubmed/29771636
http://dx.doi.org/10.1091/mbc.E17-06-0422