A genome-wide microRNA screen identifies regulators of tetraploid cell proliferation

Tetraploid cells, which are most commonly generated by errors in cell division, are genomically unstable and have been shown to promote tumorigenesis. Recent genomic studies have estimated that ∼40% of all solid tumors have undergone a genome-doubling event during their evolution, suggesting a signi...

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Detalles Bibliográficos
Autores principales: Vittoria, Marc A., Shenk, Elizabeth M., O’Rourke, Kevin P., Bolgioni, Amanda F., Lim, Sanghee, Kacprzak, Victoria, Quinton, Ryan J., Ganem, Neil J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080710/
https://www.ncbi.nlm.nih.gov/pubmed/29791254
http://dx.doi.org/10.1091/mbc.E18-02-0141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080710/
https://www.ncbi.nlm.nih.gov/pubmed/29791254
http://dx.doi.org/10.1091/mbc.E18-02-0141

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