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A genome-wide microRNA screen identifies regulators of tetraploid cell proliferation
Tetraploid cells, which are most commonly generated by errors in cell division, are genomically unstable and have been shown to promote tumorigenesis. Recent genomic studies have estimated that ∼40% of all solid tumors have undergone a genome-doubling event during their evolution, suggesting a signi...
Autores principales: | Vittoria, Marc A., Shenk, Elizabeth M., O’Rourke, Kevin P., Bolgioni, Amanda F., Lim, Sanghee, Kacprzak, Victoria, Quinton, Ryan J., Ganem, Neil J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080710/ https://www.ncbi.nlm.nih.gov/pubmed/29791254 http://dx.doi.org/10.1091/mbc.E18-02-0141 |
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