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PI(3,5)P(2) controls vacuole potassium transport to support cellular osmoregulation

Lysosomes are dynamic organelles with critical roles in cellular physiology. The lysosomal signaling lipid phosphatidylinositol 3,5-bisphosphate (PI(3,5)P(2)) is a key regulator that has been implicated to control lysosome ion homeostasis, but the scope of ion transporters targeted by PI(3,5)P(2) an...

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Detalles Bibliográficos
Autores principales: Wilson, Zachary N., Scott, Amber L., Dowell, Robin D., Odorizzi, Greg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080712/
https://www.ncbi.nlm.nih.gov/pubmed/29791245
http://dx.doi.org/10.1091/mbc.E18-01-0015