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Mechanism by which water and protein electrostatic interactions control proton transfer at the active site of channelrhodopsin
Channelrhodopsins are light-sensitive ion channels whose reaction cycles involve conformation-coupled transfer of protons. Understanding how channelrhodopsins work is important for applications in optogenetics, where light activation of these proteins triggers changes in the transmembrane potential...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080761/ https://www.ncbi.nlm.nih.gov/pubmed/30086158 http://dx.doi.org/10.1371/journal.pone.0201298 |