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Mechanism by which water and protein electrostatic interactions control proton transfer at the active site of channelrhodopsin

Channelrhodopsins are light-sensitive ion channels whose reaction cycles involve conformation-coupled transfer of protons. Understanding how channelrhodopsins work is important for applications in optogenetics, where light activation of these proteins triggers changes in the transmembrane potential...

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Detalles Bibliográficos
Autores principales: Adam, Suliman, Bondar, Ana-Nicoleta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080761/
https://www.ncbi.nlm.nih.gov/pubmed/30086158
http://dx.doi.org/10.1371/journal.pone.0201298