Searching for novel biomarkers using a mouse model of CLN3-Batten disease

CLN3-Batten disease is a rare, autosomal recessive disorder involving seizures, visual, motor and cognitive decline, and premature death. The Cln3(Δex7/8) mouse model recapitulates several phenotypic characteristics of the most common 1.02kb disease-associated deletion. Identification of reproducibl...

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Detalles Bibliográficos
Autores principales: Timm, Derek, Cain, Jacob T., Geraets, Ryan D., White, Katherine A., Koh, Seung yon, Kielian, Tammy, Pearce, David A., Hastings, Michelle L., Weimer, Jill M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080763/
https://www.ncbi.nlm.nih.gov/pubmed/30086172
http://dx.doi.org/10.1371/journal.pone.0201470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080763/
https://www.ncbi.nlm.nih.gov/pubmed/30086172
http://dx.doi.org/10.1371/journal.pone.0201470

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